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Written by Shane Hellmrich, Last Updated: November 2025 | Fact Checked | Cite This Research
What Is Vilafinil 200 MG?
Vilafinil 200 mg is a generic version of brand-name Provigil manufactured by Centurion Laboratories, a reputable Indian pharmaceutical company. Each tablet contains 200 mg of pure modafinil, the same active ingredient used in prescription wakefulness-promoting agents worldwide.
Vilafinil is approved for treating excessive daytime sleepiness associated with narcolepsy, obstructive sleep apnea, and shift work sleep disorder. Beyond its medical applications, it has gained popularity among healthy individuals seeking cognitive enhancement for demanding work, study, or creative projects.
Vilafinil Benefits: Promotes sustained wakefulness and alertness for 12-15 hours, enhances cognitive function including memory, focus, and mental processing, improves mood and motivation, reduces fatigue without the jitters of caffeine, and supports executive function for complex tasks and decision-making.
How Does Vilafinil Work?
While the exact mechanism of modafinil is not fully understood, research has identified several key pathways through which Vilafinil produces its effects. The primary mechanism involves inhibiting dopamine reuptake, which increases extracellular dopamine levels in brain regions critical for focus, motivation, and the sleep-wake cycle.
Vilafinil also modulates histamine, norepinephrine, and orexin neurotransmitter systems. This multi-pathway approach promotes wakefulness and cognitive enhancement without the harsh stimulant effects of amphetamines. Users typically describe feeling naturally alert and focused rather than artificially wired [1].
The result is enhanced blood flow to brain regions responsible for executive function, improved memory consolidation and recall, heightened alertness and mental acuity, and increased motivation to tackle challenging tasks.
Vilafinil Dosage Guidelines
The recommended dose of Vilafinil is 100-200 mg taken once daily. Most users find 200 mg optimal, though some prefer starting with 100 mg to assess their individual response before increasing if needed.
How to Take Vilafinil: For narcolepsy and sleep apnea, take 200 mg in the morning upon waking. For shift work disorder, take one hour before your shift begins. For cognitive enhancement, take in the morning or early afternoon. Swallow with water on an empty stomach for fastest absorption. Fatty foods may delay onset by up to one hour.
Effects typically begin within 30-60 minutes and reach peak concentration in 2-4 hours. Cognitive enhancement lasts 12-15 hours, so avoid taking Vilafinil after early afternoon to prevent interference with nighttime sleep.
Side Effects and Safety
Vilafinil is considered safe when taken by healthy adults as directed. Many users report that Vilafinil causes fewer side effects compared to other modafinil brands, though individual experiences vary.
Possible Side Effects: Headache (most common, often prevented by hydration), stuffy or runny nose, indigestion or diarrhea, backache, dizziness, anxiety or nervousness, difficulty sleeping, and nausea. These symptoms typically fade with continued use.
Rare but serious side effects include severe skin reactions, irregular heartbeat, dark urine, and swelling of the face or throat. Discontinue use immediately and seek medical help if you experience any severe reactions. Do not stop Vilafinil suddenly as this may cause withdrawal symptoms.
Drug Interactions
Vilafinil can interact with several medications and substances. Always inform your healthcare provider about all medications you are taking before starting Vilafinil.
Notable interactions include hormonal birth control (Vilafinil may reduce effectiveness), MAO inhibitors, warfarin and other blood thinners, CYP2C19 and CYP3A4/5 substrates, and certain antidepressants. Avoid alcohol while taking Vilafinil as it may increase side effects. Most foods work well with Vilafinil, though fatty meals may delay absorption.
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Frequently Asked Questions
How does Vilafinil compare to other modafinil brands?
Vilafinil contains the same 200 mg of modafinil as Modalert, Modvigil, and other generics. Some users report Vilafinil causes fewer side effects, though responses vary individually. It offers excellent value from a reputable manufacturer.
Who makes Vilafinil?
Vilafinil is manufactured by Centurion Laboratories, an established Indian pharmaceutical company known for producing high-quality generic medications that meet international standards.
Can Vilafinil help with ADHD?
While not officially approved for ADHD, modafinil is sometimes prescribed off-label for attention deficit conditions. Consult your healthcare provider to determine if Vilafinil is appropriate for your situation.
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References
[1] Minzenberg MJ, Carter CS. Modafinil: a review of neurochemical actions and effects on cognition. Neuropsychopharmacology. 2008;33(7):1477-1502.
Medical Disclaimer: The information provided on this page is for educational purposes only and is not intended as medical advice. Modafinil is a prescription medication in many countries. Always consult with a qualified healthcare provider before starting any new medication.
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